There is only one file type that uses the .TFC extension:
Unreal Engine 3 Texture File Cache
3D model file used by games developed with the Unreal Engine 3 technology; contains streamed textures used for applying the surface appearance to 3D models, such as characters or other game objects.
Example game that use Unreal Engine 3 include Batman: Arkham City.
NOTE: For Unreal Engine 3 developers, TFC files can be checked for errors with verifytfc, a utility included with the SDK.
Updated: February 1, 2014